Alcohol can indeed interfere with antibiotic metabolism. When alcohol is consumed alongside antibiotics, it can potentially reduce the effectiveness of the medication. The interaction between alcohol and antibiotics can vary depending on the specific antibiotic being used. Some antibiotics may cause unpleasant side effects when combined with alcohol, such as nausea, vomiting, headache, rapid heartbeat, and liver damage. It is generally advisable to avoid alcohol while taking antibiotics to ensure the medication works as intended and to prevent any adverse reactions [3][2][1].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ALCOHOL
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761694/
[3] https://pubmed.ncbi.nlm.nih.gov/387374/