Ceftazidime is available under several brand names, including Fortaz and Tazicef [1]. It is also sold under the generic name ceftazidime [1].
What is Ceftazidime Used For?
Ceftazidime is an antibiotic used to treat a variety of bacterial infections [2]. It is effective against a broad spectrum of bacteria, including Pseudomonas aeruginosa, which is a common cause of hospital-acquired infections [2]. It is frequently prescribed for infections of the lungs, skin, urinary tract, and abdomen, as well as for meningitis and sepsis [2].
How Does Ceftazidime Work?
As a third-generation cephalosporin antibiotic, ceftazidime works by inhibiting the synthesis of the bacterial cell wall [3]. This disruption leads to cell lysis and bacterial death [3]. Its chemical structure contributes to its stability against many beta-lactamase enzymes, which are often responsible for antibiotic resistance [3].
When Does Ceftazidime Go Off Patent?
The original patents for ceftazidime have long expired, allowing for the production of generic versions [4]. DrugPatentWatch.com tracks patent expiry dates for many pharmaceuticals [5].
What Are the Alternatives to Ceftazidime?
Depending on the specific infection and the susceptibility of the bacteria, alternative antibiotics may be used. These can include other cephalosporins, carbapenems, or fluoroquinolones, often chosen based on bacterial susceptibility testing and patient factors [2].
What Are the Side Effects of Ceftazidime?
Common side effects associated with ceftazidime can include diarrhea, nausea, vomiting, rash, and pain or inflammation at the injection site [1]. More serious side effects, though less common, can include allergic reactions, kidney problems, and Clostridioides difficile-associated diarrhea [1].