Based on the available information, it is recommended to consult a healthcare professional before using decongestants with Lipitor (atorvastatin). According to Drugs.com, there is a moderate interaction between decongestants and Lipitor, which means the effects of one or both of the medications could be altered [${3}].

Decongestants, such as pseudoephedrine and phenylephrine, work by narrowing blood vessels in the nasal passages, which can help alleviate congestion [${3}]. Lipitor, on the other hand, is a statin medication used to lower cholesterol levels [${1}].

The interaction between decongestants and Lipitor occurs because decongestants can increase the levels of atorvastatin in the blood, which could increase the risk of side effects such as muscle pain and liver damage [${3}]. The National Health Service (NHS) advises that atorvastatin should be used with caution when taken with other medications that can increase the risk of muscle damage [${2}].

Therefore, it is important to consult a healthcare professional before using decongestants with Lipitor to determine if it is safe and appropriate for an individual's specific medical situation. They may recommend alternative treatments or adjust the dosage of Lipitor to minimize the risk of interactions [${3}].

In summary, based on the available information, it is recommended to consult a healthcare professional before using decongestants with Lipitor due to a potential interaction that could increase the risk of side effects.

Sources:

* <https://www.drugpatentwatch.com/p/tradename/LIPITOR>
* <https://www.nhs.uk/medicines/atorvastatin/taking-atorvastatin-with-other-medicines-and-herbal-supplements/>
* <https://www.drugs.com/drug-interactions/decongestant-cold-formula-with-lipitor-857-7494-276-128.html>