Yes, certain drugs should be avoided or used with caution in conjunction with Tigecycline. According to the Mayo Clinic, Tigecycline can reduce the effectiveness of hormonal contraceptives, and patients should consider using additional or alternative forms of birth control while taking Tigecycline [${2}]. The same source also states that Tigecycline should be used with caution in patients with impaired liver function, as it may not be effectively cleared from the body [${2}].
Furthermore, a study published in the National Center for Biotechnology Information found that the concurrent use of Tigecycline and other antibiotics, such as piperacillin-tazobactam and imipenem, may increase the risk of developing C. difficile-associated diarrhea [${3}]. Therefore, it is important to be aware of the potential interactions between Tigecycline and other medications.
In summary, patients taking Tigecycline should avoid hormonal contraceptives, use caution when taking Tigecycline with impaired liver function, and be aware of the potential increased risk of developing C. difficile-associated diarrhea when taking Tigecycline with other antibiotics.
Sources:
[1] <https://www.drugpatentwatch.com/p/tradename/TIGECYCLINE>
[2] <https://www.mayoclinic.org/drugs-supplements/tigecycline-intravenous-route/precautions/drg-20072556?p=1>
[3] <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1426172/>