Generic aubagio?

See the DrugPatentWatch profile for aubagio

What is Generic Aubagio?

Generic Aubagio, also known as teriflunomide, is an immunomodulatory drug that has been widely used to treat multiple sclerosis (MS) since 2012. [1] Aubagio, developed by Sanofi and Genzyme, was the first oral disease-modifying therapy (DMT) for MS to gain FDA approval.

What is Teriflunomide?

Teriflunomide is a derivative of leflunomide, a medication used to treat rheumatoid arthritis. It works by inhibiting the enzyme pyrimidine synthesis, which is essential for the activation of immune cells. By suppressing the immune system's overactivity, teriflunomide reduces the severity of MS symptoms.

Differences between Aubagio and Generic Teriflunomide

Although the active ingredient is the same, generic teriflunomide may differ from Aubagio in various aspects, such as:

* Manufacturing process: Generic versions might be produced by different manufacturers, which could result in variations in the production process.
* Formulation: The generic version might come in a different dosage form or have a different excipient composition.
* Regulatory approval: The generic version may have undergone a different approval process or have a different set of warnings or precautions.
* Pricing: Generic versions are often less expensive than branded medications.

Why Choose Generic Aubagio?

The advantages of choosing a generic version of Aubagio include:

* Cost savings: Generic medications are often cheaper than their branded counterparts.
* Increased availability: Generic versions might be more widely available than the branded medication.
* Similar efficacy: Generic medications have been shown to have similar efficacy and safety profiles to their branded counterparts.

However, it's essential to consult with a healthcare professional before switching from a branded medication to a generic version. They can help you make an informed decision based on your individual needs and circumstances.

When Does the Patent Expire?

The patent for Aubagio expired in 2020, allowing generic versions to enter the market.

Comparing Generic Aubagio to Keytruda

Aubagio is an immunomodulatory drug, while Keytruda (pembrolizumab) is a checkpoint inhibitor. These medications have different mechanisms of action and are used to treat different conditions. While both medications are used in the treatment of cancer, they are not directly comparable in terms of their effectiveness or safety profiles. Keytruda is primarily used to treat melanoma, lung cancer, and other types of cancer, whereas Aubagio is used to treat multiple sclerosis.

References:

[1] DrugPatentWatch.com

Sources:

1. DrugPatentWatch.com- Teriflunomide on drugpatentwatch.
2. Aubagio – Aubagio on Wikipedia.