Does Lyrica (pregabalin) change heart rate?
Lyrica (pregabalin) can affect how your heart feels during treatment. Prescribing information reports cardiovascular effects that can include changes in heart rate, and it may cause symptoms some people describe as palpitations (an awareness of a faster or more forceful heartbeat) [1].
What heart-related symptoms should patients watch for?
People taking Lyrica should pay attention to any new or worsening symptoms that could suggest a heart-rate or rhythm issue, such as palpitations, fast heartbeat, or feeling lightheaded or faint. Seek urgent care if symptoms are severe, come with chest pain, trouble breathing, or fainting [1].
Can Lyrica cause palpitations, tachycardia, or rhythm problems?
The drug is associated with cardiovascular side effects reported in clinical use, including cases where patients experience palpitations and other heart-rate-related sensations [1]. If you notice a clear pattern (for example, symptoms starting after dose increases), contact your prescriber promptly.
Who is at higher risk of heart-rate problems on Lyrica?
Risk can be higher if you already have cardiovascular disease, heart rhythm problems, or you take other medicines that also affect heart rate or blood pressure. Your prescriber can assess your specific risk profile based on your medical history and medication list [1].
Does dose or starting it make symptoms more likely?
Heart-related side effects can occur after starting and can also show up after dose changes. If palpitations or an unusually fast heartbeat begins after a dose adjustment, it is important to report it to your prescriber right away [1].
Are there drug interactions that can raise heart-rate risk?
Yes. Lyrica can interact with other medications that affect the nervous system, sedation level, or cardiovascular status, which can indirectly worsen symptoms like dizziness or lightheadedness that people sometimes interpret as heart-rate changes. Your pharmacist or prescriber can check for interactions with your current medicines [1].
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Sources
[1] https://www.drugs.com/sfx/lyrica-side-effects.html