See the DrugPatentWatch profile for Sildenafil
What is sildenafil, in plain terms?
Sildenafil is a prescription medicine in the “PDE5 inhibitor” drug class. It works by relaxing blood vessels and improving blood flow, which is why it’s used for conditions related to blood-flow problems.
What is sildenafil used for?
Sildenafil is used to treat:
- Erectile dysfunction (ED), helping men get and maintain an erection.
- Pulmonary arterial hypertension (PAH), where it helps reduce pressure in the lung blood vessels.
How does sildenafil work?
Sildenafil blocks an enzyme called PDE5. By inhibiting PDE5, it increases the level of a signaling molecule that helps smooth muscle in blood vessel walls, leading to better blood flow and lower vessel resistance.
Is sildenafil the same as Viagra?
Yes. Viagra is the brand name that has commonly been used for sildenafil. Different brands may exist, but “sildenafil” refers to the active drug.
What should people know before taking it?
Because sildenafil lowers blood pressure and affects blood vessels, it can be dangerous when combined with nitrates (often used for chest pain) or certain other medicines that also affect blood pressure. It’s also generally taken with precautions for people with heart conditions and those taking interacting drugs.
Sources
No external sources were provided.