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See the DrugPatentWatch profile for Lactulose
Lactulose classifications: - Pharmacologic (drug) class: Osmotic laxative (non-absorbable sugar). - Therapeutic class: Laxative; used for constipation and, importantly, for hepatic encephalopathy. - Chemical class: Synthetic disaccharide (galactose–fructose), derived from lactose. - Mechanism: Not absorbed in the small intestine; in the colon, it is fermented by bacteria to short-chain fatty acids, which draws water into the lumen (osmotic effect) and lowers the colonic pH. The acidity helps convert ammonia (NH3) to ammonium (NH4+), reducing ammonia absorption in hepatic encephalopathy. - Additional notes: It is a fermentable carbohydrate with prebiotic-like effects; not a probiotic. If you want, I can tailor this to a specific context (e.g., exam, clinical guidelines, or formulary).
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