Standard Orencia Infusion Schedule for Adults
Orencia (abatacept) infusions for adults with moderate to severe rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis follow this regimen: one 30-minute infusion at weeks 0, 2, and 4, then every 4 weeks.[1]
How Dosing Is Calculated
Dose depends on body weight: 500 mg for under 60 kg, 750 mg for 60-100 kg, and 1,000 mg for over 100 kg. It's given intravenously by a healthcare provider.[1]
Differences for Subcutaneous Injections
Adults can switch to weekly self-injections (125 mg) after the initial two infusions (weeks 0 and 4), skipping the week 2 dose. This option suits those preferring home administration over clinic visits.[1]
Adjustments for Other Conditions
No changes for polyarticular juvenile idiopathic arthritis in adults, but it's not approved for kids under subcutaneous form. Kidney or liver issues don't require dose tweaks.[1]
Common Patient Questions on Frequency
Missing a dose? Get it as soon as possible, then resume schedule—don't double up. Infusions every 4 weeks help maintain steady drug levels to control inflammation.[1]
[1]: https://www.orencia.com/rheumatoid-arthritis/treatment-dosing (official prescribing information summary)