Lipitor is a medication used to lower cholesterol levels in the body. According to Drug Patent Watch [1], the active ingredient in Lipitor is atorvastatin calcium. It is important to note that certain natural supplements may interact with Lipitor and affect its efficacy. SingleCare [2] warns that St. John's Wort, a supplement commonly used to treat depression, can decrease the effectiveness of Lipitor. Additionally, ConsumerLab [3] states that red yeast rice supplements, which also lower cholesterol levels, should not be taken with statins like Lipitor, as it may increase the risk of side effects. It is important to speak with a healthcare provider before taking any natural supplements while on Lipitor to avoid any potential interactions or adverse effects.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.singlecare.com/blog/atorvastatin-interactions/
[3] https://www.consumerlab.com/answers/which-drugs-should-be-avoided-when-taking-statins/statin-supplement-interactions/