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Apotex’s specific changes to the ruxolitinib formulation (for example, differences in tablet composition, coatings, excipients, dissolution/particle properties, or manufacturing process) are not provided in the information available here. Without the underlying document or claim text that describes Apotex’s formulation work, I can’t accurately state what changed.
To identify “what changes” Apotex made, you generally need one of the following: - The relevant patent/application describing Apotex’s formulation or ruxolitinib generic product changes. - The regulatory filing or technical dossier (often including composition and in vitro dissolution information). - A lawsuit or regulatory dispute document quoting the exact differences (common in patent litigation summaries).
If you paste or upload the excerpt (or provide a link/title to the document) that mentions Apotex and ruxolitinib, I can extract and summarize the exact formulation changes it describes, including the specific components/process terms used.
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