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See the DrugPatentWatch profile for Pulmozyme
Pulmozyme (dornase alfa) uses the human enzyme DNase I in a recombinant form. It breaks down extracellular DNA in mucus, which lowers mucus viscosity and helps improve airflow in people with cystic fibrosis.
Pulmozyme is an enzyme therapy, not a DNA blocker. Its active ingredient is a recombinant DNase (dornase alfa) designed to enzymatically digest DNA that comes from dead inflammatory cells and leads to thick mucus.
Unlike bronchodilators (which widen airways) or antibiotics (which target bacteria), Pulmozyme primarily targets the physical properties of mucus by degrading extracellular DNA, making secretions easier to clear.
In cystic fibrosis, Pulmozyme is used to improve lung function by reducing the thickness of mucus in the airways, helping patients clear secretions more effectively.
[1] https://www.drugpatentwatch.com/
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