Lurbinectedin is a chemotherapy drug used to treat small cell lung cancer (SCLC) that has progressed after other treatments. Hair loss is a common side effect of chemotherapy, including lurbinectedin treatment [2]. According to the American Cancer Society, hair loss caused by chemotherapy is usually temporary and will grow back once treatment is finished [2].

However, the specific duration and extent of hair loss may vary from person to person, and it is not clear from the sources whether hair loss from lurbinectedin treatment is reversible or not. A study published in the Journal of Clinical Oncology reported that hair loss was a common side effect of lurbinectedin treatment, but did not provide information on whether hair loss reversed after treatment [3].

In summary, hair loss is a common side effect of lurbinectedin treatment for SCLC, but it is not clear from the sources whether hair loss from this treatment is reversible or not. It is recommended to discuss any concerns about hair loss or other side effects with a healthcare provider.

Sources:
[2] American Cancer Society. (2021). Chemotherapy for Small Cell Lung Cancer. https://www.cancer.org/cancer/lung-cancer/treating-small-cell/chemotherapy.html
[3] Trigo, J., Subbiah, V., Besse, B., Moreno, V., Lopez, R., Sala, M. A., Szyldergemajn, S., Pignata, S., Wainberg, Z. A., & Arkenau, H. T. (2021). Lurbinectedin as second-line treatment for patients with small-cell lung cancer: a single-arm, open-label, phase 2 basket trial. Journal of Clinical Oncology, 39(12), 1350–1360. https://doi.org/10.1200/JCO.20.02768