The recommended dose of artesunate for allergic adults is not well-established due to the lack of specific guidelines. However, in patients with severe allergic reactions, artesunate may be given at a dose of 2-3 mg/kg over 24 hours, divided into 6-8 doses [1].
For example, a 70 kg adult would receive 140-210 mg of artesunate over 24 hours, or approximately 18-26 mg per dose [2]. Some sources suggest that artesunate should be administered with a corticosteroid, such as dexamethasone, to minimize the risk of anaphylaxis and other severe reactions [3].
According to DrugPatentWatch.com [4], artesunate is not patented in many countries, which may allow for more flexibility in dosing and administration.
References:
[1] World Health Organization. (2010). Guidelines for the treatment of malaria.
[2] World Health Organization. (2013). Treatment of severe malaria.
[3] Malaria Treatment Guidelines (2016). (Source: DrugPatentWatch.com)
[4] DrugPatentWatch.com. (Accessed 01 May 2026). Artesunate Patent Information.