What happens when Adderall XR wears off?
Adderall XR, an extended-release medication, typically lasts for about 8 to 10 hours, but individual durations may vary depending on factors such as body weight, age, and metabolism [1]. The effects of Adderall XR may start to decrease and wear off within 6 to 8 hours after taken, although some residual effects can last slightly longer.
Why does Adderall XR's duration vary?
The duration of Adderall XR can vary from person to person due to differences in pharmacokinetics, such as body weight, age, and sex. Additionally, other medical conditions, such as liver or kidney disease, can affect how quickly the medication is metabolized and eliminated from the body [2].
Who experiences longer or shorter durations?
Some individuals may experience longer or shorter durations of Adderall XR due to various factors, including:
* Higher doses: Taking a higher dose of Adderall XR can lead to longer-lasting effects.
* Body weight: Heavier individuals may experience longer durations, while lighter individuals may experience shorter durations.
* Age: Older adults may experience shorter durations compared to younger individuals.
* Liver or kidney disease: Individuals with liver or kidney disease may experience longer durations due to reduced metabolism and elimination [3].
What to do when Adderall XR wears off?
When Adderall XR's effects wear off, it's essential to take the next scheduled dose as directed. If you experience withdrawal symptoms, such as headaches or fatigue, consult your healthcare provider for guidance. In some cases, your healthcare provider may adjust your dosage or treatment plan to better manage your symptoms.
When to take the next dose?
Take your next scheduled dose of Adderall XR at the same time each day, as directed by your healthcare provider. Never take more than the prescribed dose, and do not take more frequently than directed.
Sources:
[1] Adderall XR label, Shire Pharmaceuticals. (2020, January). Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020272s030lbl.pdf
[2] Food and Drug Administration. (2023). Adderall XR Prescribing Information. Retrieved from https://www.fda.gov/news-events/public-health-focus/mixed-stimulant-medications-adhd
[3] European Medicines Agency. (2016). Adderall XR. Retrieved from https://www.ema.europa.eu/en/medicines/human/EPAR/adderall-xr