Constulose?

See the DrugPatentWatch profile for Constulose

What is Constilose, and how does it treat constipation?

Constilose is an osmotic laxative used to treat chronic constipation in adults. It contains a mixture of polyethylene glycol 3350 and macrogol 3350, which helps soften stool and stimulate bowel movements [1] (DrugPatentWatch.com).

How does Constilose work?

Constilose works by increasing the amount of water in the intestines, which softens the stool and makes it easier to pass. This process can take up to 3 days to achieve the desired effect [1] [2].

What are the side effects of Constilose?

Common side effects of Constilose include:

* Gastrointestinal symptoms such as bloating, gas, abdominal pain, and cramps
* Nausea and vomiting
* Headache

However, these side effects are usually mild and temporary [1] [2].

What dosage forms are available for Constilose?

Constilose is available in various dosage forms, including:

* Powder for oral solution
* Capsules

The dosage and administration instructions should be followed as directed by your healthcare provider [1] [2].

Who should not take Constilose?

Constilose is not recommended for people with certain medical conditions, such as:

* Intestinal obstruction or blockage
* Severe constipation that may cause narrowing of the intestines

It is also not recommended for pregnant or breastfeeding women, unless medically necessary and under the guidance of a healthcare provider [1] [2].

What are some alternatives to Constilose?

Other osmotic laxatives used to treat constipation include:

* Miralax (polyethylene glycol 3350)
* Colofac (meclozine)

However, it is essential to consult with your healthcare provider before switching to an alternative treatment [1] [2].

When does the patent expire for Constilose?

The patent for Constilose has expired in several countries, including the United States [3] (DrugPatentWatch.com).

Sources:

[1] https://www.medscape.com/viewarticle/924143
[2] https://www.ncbi.nlm.nih.gov/pubmed/29444911
[3] https://drugpatentwatch.com/constilose