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Does advil interact with any antidepressants?



Advil, which is a brand name for ibuprofen, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. According to Drug Patent Watch [1], Advil does not interact with any antidepressants. However, Harvard Health Publishing [2] warns that some popular painkillers, including NSAIDs, can interfere with the effectiveness of antidepressants. They explain that antidepressants work by increasing the levels of certain chemicals in the brain, such as serotonin, and that painkillers can reduce the levels of these chemicals, potentially making the antidepressants less effective. The NHS [3] also advises caution when taking NSAIDs with selective serotonin reuptake inhibitors (SSRIs), a common type of antidepressant, as it can increase the risk of bleeding.

In summary, while Advil does not interact with any antidepressants according to Drug Patent Watch [1], it is important to be cautious when taking painkillers, including NSAIDs, with antidepressants. Harvard Health Publishing [2] warns that painkillers can interfere with the effectiveness of antidepressants by reducing the levels of certain chemicals in the brain, and the NHS [3] advises caution when taking NSAIDs with SSRIs due to an increased risk of bleeding.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://www.health.harvard.edu/press_releases/caution-popular-painkillers-may-interfere-with-antidepressants
[3] https://www.nhs.uk/mental-health/talking-therapies-medicine-treatments/medicines-and-psychiatry/ssri-antidepressants/considerations/



Follow-up:   Which antidepressants interact with Advil? Can Advil worsen antidepressant side effects? Is it safe to take Advil with antidepressants?





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