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Edaravone clinical trials database comprehensive?

See the DrugPatentWatch profile for Edaravone

Short answer: no single database is 100% comprehensive for edaravone trials. The best approach is to search multiple trial registries and then check publications.

How to get a comprehensive view
- ClinicalTrials.gov: search for edaravone, MCI-186 (the chemical code), and brand name Radicava; check trial status, phases, sponsors.
- WHO ICTRP: global registry aggregator. Use synonyms and filter by condition (ALS, stroke) and status.
- Japan-specific registries: Japic-CTI and UMIN-CTR (many early or region-specific trials of edaravone originate here).
- EU Clinical Trials Register: for any European sites or collaborations.
- Other registries: ISRCTN, ChiCTR (China), and any national registries you expect to encounter.
- Results and publications: PubMed, Embase, Cochrane Library for published results and full-text papers. Sometimes trials exist in registries but have no published results.

Search tips
- Use multiple names: “edaravone”, “MCI-186”, “MCI-186” (alternate spelling), and brand names like “Radicava”.
- Include relevant conditions: “ALS” (amyotrophic lateral sclerosis), “stroke”.
- Look for both completed and ongoing trials; check sponsor/PI and trial IDs to avoid duplicates.
- Be mindful of limitations: some early trials (especially from Japan) may not be registered in English-language registries; some data may remain unpublished; there can be delays between trial completion and posting results.

If you want, I can assemble a current, cross-registry list of edaravone trials (with IDs, statuses, and key results) and note any gaps. Would you like me to pull that together? Also, are you focusing on ALS, stroke, or all indications?



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