Lipitor, which is the brand name for atorvastatin, is a medication used to lower cholesterol levels in the blood. According to Drug Patent Watch [1], Lipitor works by inhibiting an enzyme called HMG-CoA reductase, which is responsible for producing cholesterol in the liver. By doing so, Lipitor can reduce the amount of cholesterol in the bloodstream, which can lower the risk of heart disease.

While Lipitor can effectively lower cholesterol levels, it may also affect the digestion of fatty meals, especially in people who have had their gallbladder removed. The gallbladder is a small organ that stores bile, a substance produced by the liver that helps break down fats in the small intestine. Without a gallbladder, the liver continuously produces bile, which can lead to diarrhea, bloating, and other digestive issues after consuming fatty meals [2].

However, according to the Cleveland Clinic [3], consuming foods that are high in phytosterols, sterols, and stanols can help reduce the absorption of cholesterol in the small intestine, which can be beneficial for people taking Lipitor. These compounds are naturally occurring substances found in plants, and they have a similar structure to cholesterol. When consumed, they can compete with cholesterol for absorption in the small intestine, which can lead to lower cholesterol levels in the bloodstream.

In summary, Lipitor can affect the digestion of fatty meals, especially in people who have had their gallbladder removed. However, consuming foods that are high in phytosterols, sterols, and stanols can help reduce the absorption of cholesterol in the small intestine, which can be beneficial for people taking Lipitor. It is important to consult with a healthcare provider to determine the best course of action for managing cholesterol levels and any associated digestive issues.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.everydayhealth.com/gallbladder/living-without-a-gallbladder.aspx
[3] https://my.clevelandclinic.org/health/articles/17368-phytosterols-sterols--stanols