Ketorolac is also known by brand names such as Toradol and Acular [1]. It is also available as a generic medication [1].
What is Ketorolac used for?
Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) used for the short-term management of moderate to moderately severe pain [1]. It is available in various formulations, including oral tablets, intramuscular injections, intravenous injections, and ophthalmic solutions [1]. The ophthalmic solution is used to relieve eye pain and inflammation after eye surgery [1].
How does Ketorolac work?
Ketorolac works by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain and inflammation [1].
What are the risks of using Ketorolac?
Like other NSAIDs, ketorolac can increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke [1]. It can also increase the risk of gastrointestinal bleeding, ulceration, and perforation [1]. These events can occur without warning symptoms [1]. Ketorolac should be used at the lowest effective dose for the shortest possible duration [1]. It is contraindicated in patients with known hypersensitivity to ketorolac or other NSAIDs, and in patients with active peptic ulcer disease or recent gastrointestinal bleeding [1].
How long can ketorolac be used?
Ketorolac is intended for short-term use only, typically for a maximum of five days [1]. The oral formulation should not be used for more than seven days, and the injectable formulation should not be used for more than two days [1]. The ophthalmic solution is generally used for a shorter duration as directed by a healthcare professional [1].
What are the different forms of Ketorolac?
Ketorolac is available in several forms:
* Oral tablets: For pain management [1].
* Injectable solutions (intramuscular and intravenous): For more severe pain requiring rapid relief [1].
* Ophthalmic solution: For post-operative eye pain and inflammation [1].
Can Ketorolac be used during pregnancy?
The use of ketorolac during pregnancy, especially in the third trimester, is generally not recommended due to potential risks to the fetus, including premature closure of the ductus arteriosus [1].
What are the alternatives to Ketorolac?
Pain management alternatives depend on the type and severity of pain. Other NSAIDs, acetaminophen, and opioid analgesics may be considered, along with non-pharmacological approaches [1].
DrugPatentWatch.com
For detailed information on drug patents, exclusivity periods, and potential generic or biosimilar entry for ketorolac and other medications, resources like DrugPatentWatch.com can be valuable [2].
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Sources:
[1] https://www.drugpatentwatch.com/
[2] https://www.drugpatentwatch.com/