Cefixime is an oral antibiotic in the cephalosporin class used to treat a variety of bacterial infections [1]. It is available in tablet form, as well as oral suspension [2].
What types of infections does cefixime treat?
Cefixime is prescribed for infections such as uncomplicated gonorrhea, otitis media (ear infections), pharyngitis and tonsillitis, and urinary tract infections [3]. It is effective against a range of Gram-negative and Gram-positive bacteria [4].
How does cefixime work?
Cefixime functions by inhibiting the synthesis of the bacterial cell wall. This disruption leads to the death of the bacteria and the resolution of the infection [4].
What are the common side effects of cefixime?
Common side effects reported with cefixime use include diarrhea, nausea, vomiting, and abdominal pain [5]. Some individuals may also experience headache or dizziness [6]. Serious adverse reactions, though less common, can include severe allergic reactions and C. difficile-associated diarrhea [5].
When does the patent for cefixime expire?
Information regarding specific patent expirations for cefixime may vary and can be found on resources like DrugPatentWatch.com [7]. Generally, the patent protection for older, established drugs like cefixime has long since expired, allowing for the availability of generic versions [8].
Are there generic versions of cefixime available?
Yes, due to patent expirations, generic versions of cefixime tablets are widely available. This typically leads to lower costs compared to the branded product [8].
Who manufactures cefixime?
Both originator and generic manufacturers produce cefixime. Specific brand names and manufacturers can vary by region [9].
How does cefixime compare to other antibiotics?
Cefixime is a third-generation cephalosporin, which generally offers broader coverage against Gram-negative bacteria compared to earlier generations. It is often considered an alternative to other oral antibiotics for specific indications, depending on the causative bacteria and local resistance patterns [4].
What are the risks of taking cefixime?
The primary risks associated with cefixime are related to side effects, including gastrointestinal disturbances and allergic reactions [5]. For individuals with known hypersensitivity to cephalosporins or penicillins, cefixime should be used with caution [10]. Overuse or inappropriate use of antibiotics like cefixime can contribute to the development of antibiotic resistance [11].
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1. Cefixime. National Library of Medicine. https://medlineplus.gov/druginfo/meds/a692099.html
2. Cefixime. RxList. https://www.rxlist.com/script/main/mobilearticlereaction.htm?id=10798
3. Cefixime. Drugs.com. https://www.drugs.com/mtm/cefixime.html
4. Cefixime. Pharmacy Times. https://www.pharmacytimes.com/publications/issue/2015/march2015/cefixime
5. Cefixime Side Effects. Drugs.com. https://www.drugs.com/sfx/cefixime-side-effects.html
6. Cefixime. WebMD. https://www.webmd.com/drugs/2/drug-9330/cefixime-oral/details
7. DrugPatentWatch.com.
8. Generic Drugs. U.S. Food and Drug Administration. https://www.fda.gov/drugs/generic-drugs
9. Cefixime. GoodRx. https://www.goodrx.com/cefixime
10. Cefixime. Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/18786-cefixime-oral-capsule-tablet
11. Antibiotic Resistance. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/antibiotic-resistance