Is skyrizi a biologic?

Is Skyrizi considered a biologic?

Yes. Skyrizi (risankizumab) is a biologic medicine. It’s an antibody-based therapy designed to block specific inflammation pathways in conditions like plaque psoriasis and psoriatic arthritis. [1]

Why does Skyrizi count as a “biologic” rather than a typical drug?

Skyrizi is a monoclonal antibody (a lab-made protein that targets a specific molecule in the immune system), which is what places it in the biologic drug class rather than a small-molecule medication. [1]

What kind of biologic is it?

Skyrizi is a monoclonal antibody biologic. It targets interleukin-23 (IL-23). [1]

What does that mean for patients who are comparing biologics?

If you’re comparing it to other treatments, Skyrizi falls in the same broad category as other antibody biologics used for immune-mediated inflammatory diseases (like psoriasis), not in the category of standard non-biologic oral drugs. [1]

Sources
[1] https://www.skyrizi.com/psoriasis (Skyrizi prescribing information/brand site identifying risankizumab as a monoclonal antibody)