Is trintellix an ssri?

Is Trintellix an SSRI?

No. Trintellix (vortioxetine) is not an SSRI. It is an antidepressant with a different pharmacologic profile that includes serotonin reuptake inhibition plus additional actions at several serotonin receptor subtypes, rather than behaving like a classic selective serotonin reuptake inhibitor (SSRI).

What kind of antidepressant is Trintellix, then?

Vortioxetine is commonly grouped as a serotonin modulator and stimulator. Its receptor activity helps distinguish it from standard SSRIs, which primarily work by selectively blocking serotonin reuptake.

How is it different from typical SSRIs people compare it to?

Typical SSRIs include drugs like sertraline, fluoxetine, citalopram, and escitalopram. Those medications mainly act by inhibiting serotonin reuptake, while vortioxetine also modulates multiple serotonin receptors, leading to a different overall mechanism than “SSRI-only” drugs.