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No. Trintellix (vortioxetine) is not an SSRI. It is an antidepressant with a different pharmacologic profile that includes serotonin reuptake inhibition plus additional actions at several serotonin receptor subtypes, rather than behaving like a classic selective serotonin reuptake inhibitor (SSRI).
Vortioxetine is commonly grouped as a serotonin modulator and stimulator. Its receptor activity helps distinguish it from standard SSRIs, which primarily work by selectively blocking serotonin reuptake.
Typical SSRIs include drugs like sertraline, fluoxetine, citalopram, and escitalopram. Those medications mainly act by inhibiting serotonin reuptake, while vortioxetine also modulates multiple serotonin receptors, leading to a different overall mechanism than “SSRI-only” drugs.
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