What side effects can ibuprofen (Advil) cause?
Ibuprofen (Advil) is an NSAID (nonsteroidal anti-inflammatory drug). Common side effects are usually related to the stomach and can include indigestion, heartburn, nausea, and stomach pain. [1]
Some people may also experience dizziness or headache while taking ibuprofen. [1]
What are the more serious ibuprofen (Advil) side effects to watch for?
Serious risks include bleeding in the stomach or intestines, which can be life-threatening. Watch for signs such as black, tarry stools; vomiting blood or material that looks like coffee grounds; or severe stomach pain. [1]
Other serious issues include:
- Allergic reactions, such as swelling of the face or throat, trouble breathing, or widespread rash. [1]
- Kidney problems, suggested by decreased urination or sudden weight gain from fluid retention. [1]
- Increased risk of cardiovascular events (for example, heart attack or stroke), especially with higher doses or longer use. [1]
Can ibuprofen (Advil) worsen ulcers, bleeding, or other stomach problems?
Yes. Ibuprofen can irritate the stomach lining and increase the chance of gastrointestinal bleeding and ulcers. People with a history of ulcers or GI bleeding, or those taking other medicines that raise bleeding risk, should be especially cautious. [1]
Who is at higher risk for ibuprofen (Advil) side effects?
Risk is higher for people who:
- Take ibuprofen at higher doses or for longer periods
- Have a history of stomach ulcers or GI bleeding
- Have kidney disease
- Have cardiovascular disease or multiple cardiovascular risk factors
- Use other medicines that can increase bleeding (for example, some anticoagulants or antiplatelet drugs) [1]
Drug interactions: what side effects might increase when ibuprofen (Advil) is combined with other meds?
Ibuprofen can increase bleeding risk when taken with some blood thinners or antiplatelet medications. It can also raise kidney-related risk when combined with certain drugs that affect kidney function. These interactions can lead to more severe adverse effects than ibuprofen alone. [1]
When should someone stop ibuprofen (Advil) and get medical help?
Get urgent medical care for warning signs such as:
- Trouble breathing, facial/throat swelling, or signs of severe allergic reaction
- Black/tarry stools, vomiting blood, or severe stomach pain
- Chest pain, weakness on one side, or sudden trouble speaking (possible stroke/heart attack symptoms)
- Very little urination, severe weakness, or sudden swelling [1]
How can side effects be reduced?
Using the lowest effective dose for the shortest time helps reduce risk. Taking ibuprofen with food may reduce stomach irritation for some people, though it doesn’t remove the risk of serious GI bleeding. [1]
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Sources
- https://www.drugs.com/sfx/ibuprofen-side-effects.html