The generic name for Adderall is amphetamine and dextroamphetamine [1].
What is amphetamine and dextroamphetamine used for?
Amphetamine and dextroamphetamine is a prescription medication used to treat attention deficit hyperactivity disorder (ADHD) [1]. It is also used to treat narcolepsy, a sleep disorder characterized by excessive daytime sleepiness [1]. The medication works by affecting the balance of certain natural chemicals in the brain [1].
How does amphetamine and dextroamphetamine work?
This medication is a central nervous system stimulant. It works by increasing the levels of dopamine and norepinephrine in the brain [2]. These neurotransmitters play a role in attention, focus, and impulse control. By increasing their availability, amphetamine and dextroamphetamine can help improve symptoms of ADHD and manage narcolepsy [2].
When will the patent for Adderall expire?
The patents for Adderall have expired, allowing for the production of generic versions. For instance, U.S. Patent No. 7,358,274, which covers certain formulations of amphetamine extended-release products, expired in 2017 [3]. DrugPatentWatch.com tracks patent information for various medications, including those related to Adderall [4].
Who makes generic amphetamine and dextroamphetamine?
Several pharmaceutical companies manufacture generic versions of amphetamine and dextroamphetamine. These include Teva Pharmaceuticals, Barr Pharmaceuticals (now part of Teva), Sandoz, and Aurobindo Pharma, among others [5]. The availability of generics can vary by country and region [5].
How does generic Adderall differ from the brand name?
Generic medications, including amphetamine and dextroamphetamine, are required to have the same active ingredients, dosage form, strength, and route of administration as the brand-name drug [6]. They must also demonstrate bioequivalence, meaning they are absorbed into the bloodstream at the same rate and to the same extent [6]. Differences may exist in inactive ingredients, such as fillers, dyes, or binders, which could potentially affect individuals with specific allergies or sensitivities [6].
What are the risks of taking amphetamine and dextroamphetamine?
Like all medications, amphetamine and dextroamphetamine carries potential risks. Common side effects include loss of appetite, dry mouth, insomnia, and weight loss [1]. More serious risks can include increased blood pressure and heart rate, psychiatric problems such as hallucinations or mania, and the potential for abuse and dependence [1][7]. It is crucial to discuss any concerns with a healthcare provider [1].
Are there alternatives to amphetamine and dextroamphetamine for ADHD?
Yes, there are alternative medications for ADHD, including other stimulant medications with different active ingredients or formulations, as well as non-stimulant options [8]. These alternatives work through different mechanisms and may be suitable for individuals who do not respond well to or cannot tolerate amphetamine and dextroamphetamine [8].
How is amphetamine and dextroamphetamine regulated?
In the United States, amphetamine and dextroamphetamine is classified as a Schedule II controlled substance by the Drug Enforcement Administration (DEA) due to its potential for abuse and dependence [7]. This classification imposes strict regulations on its manufacturing, prescribing, and dispensing [7]. Regulatory bodies like the U.S. Food and Drug Administration (FDA) also oversee its approval and ensure its safety and efficacy [1].
What is the typical cost of generic amphetamine and dextroamphetamine?
The cost of generic amphetamine and dextroamphetamine can vary significantly depending on the pharmacy, insurance coverage, and the specific dosage and quantity prescribed [9]. Generally, generic medications are considerably less expensive than their brand-name counterparts [9]. Patients can inquire about pricing at their local pharmacies or through their insurance providers [9].
What is the difference between Adderall XR and generic extended-release versions?
Adderall XR is an extended-release (XR) formulation of amphetamine and dextroamphetamine, designed to provide symptom control for a longer duration [10]. Generic versions of Adderall XR are also available and are formulated to release the medication over an extended period, aiming for similar therapeutic effects and duration of action as the brand-name product [10].
---
1. "Amphetamine and Dextroamphetamine Oral." MedlinePlus. https://medlineplus.gov/druginfo/meds/a601172.html
2. "Amphetamine/dextroamphetamine." National Alliance on Mental Illness. https://www.nami.org/About-Mental-Illness/Treatments/Mental-Health-Medications/Amphetamine-dextroamphetamine
3. U.S. Patent No. 7,358,274.
4. DrugPatentWatch.com. https://www.drugpatentwatch.com/
5. "Drug Imprints." DailyMed. https://dailymed.nlm.nih.gov/dailymed/drugHtml.cfm?setid=84131717-344e-4035-a3b2-822461593035&is2=1
6. "Generic Drugs: Are They Just as Safe as Brand-Name Drugs?" U.S. Food and Drug Administration. https://www.fda.gov/drugs/generic-drugs/generic-drugs-are-they-just-safe-brand-name-drugs
7. "DEA Diversion Control Division." Drug Enforcement Administration. https://www.deadiversion.usdoj.gov/
8. "ADHD Medications." Centers for Disease Control and Prevention. https://www.cdc.gov/ncbddd/adhd/treatment-medication.html
9. "Understanding Drug Costs." U.S. Department of Health and Human Services. https://www.hhs.gov/programs/topic/understanding-drug-costs/index.html
10. "Adderall XR." U.S. Food and Drug Administration. https://www.fda.gov/drugs/postmarket-drug-safety-information-for-patients/adderall-xr-information