Brand name of buprenorphine?

What is the brand name of buprenorphine?

The brand names of buprenorphine include Subutex and Suboxone [1]. Subutex is a sublingual tablet of uncoated buprenorphine, while Suboxone is a sublingual film that combines buprenorphine with naloxone, a medication that helps deter opioid misuse [2].

Key differences between Subutex and Suboxone:

Subutex is used as a monotherapy for the treatment of opioid addiction, while Suboxone is typically used as a first-line treatment for opioid use disorder, especially for individuals who have a high risk of relapse [3]. Suboxone contains naloxone, which can help prevent the misuse of buprenorphine by causing withdrawal symptoms when injected.

Other buprenorphine products:

Buprenorphine is also available in other formulations, including buccal films (Buprenex and Belbuca), extended-release injections (Sublocade), and tablets (Zubsolv) [4].

Patent and exclusivity:

The patents for Suboxone and Subutex are set to expire in 2024 [5]. This may lead to the introduction of generic or biosimilar versions of the medication.

References:

[1] FDA. (2002). Subutex labeling.
[2] FDA. (2002). Suboxone labeling.
[3] SAMHSA. (n.d.). Medications for Opioid Use Disorder.
[4] DrugPatentWatch. (n.d.). Buprenorphine.
[5] DrugPatentWatch. (n.d.). Buprenorphine Subutex, Suboxone patent expiration date.