What is the generic name for Keppra?
Keppra's generic name is levetiracetam [1].
How does levetiracetam (Keppra) work?
Levetiracetam is an antiepileptic drug used to treat partial-onset seizures, myoclonic seizures, and primary generalized tonic-clonic seizures in individuals with epilepsy [1]. Its exact mechanism of action is not fully understood, but it is believed to bind to synaptic vesicle protein 2A (SV2A) in the brain [1]. This binding is thought to modulate neurotransmitter release without affecting normal neurotransmission [1].
When did Keppra's patent expire?
The original patent for Keppra (levetiracetam) expired in 2008 in the United States [2]. This expiry opened the door for generic versions of the drug to enter the market.
Can I get levetiracetam as a generic drug?
Yes, levetiracetam is available as a generic medication. Many pharmaceutical companies now manufacture and market generic versions of Keppra [3].
Who makes generic levetiracetam?
Numerous manufacturers produce generic levetiracetam. These include companies like Teva Pharmaceuticals, Mylan (now Viatris), Accord Healthcare, and others [3]. The specific manufacturer available may depend on your pharmacy and location.
How much does generic levetiracetam cost?
The cost of generic levetiracetam is typically significantly lower than the brand-name Keppra. Prices can vary based on the dosage, quantity, pharmacy, and insurance coverage. However, generic medications generally offer substantial savings for patients [3].
What are the differences between brand-name Keppra and generic levetiracetam?
The active ingredient in both Keppra and its generic versions is levetiracetam [1, 3]. Generic drugs are required to be bioequivalent to their brand-name counterparts, meaning they have the same dosage, safety, quality, and performance [4]. The primary differences often lie in the inactive ingredients (fillers, binders, colors) and the cost, with generic versions being more affordable [3, 4].
What are the risks associated with taking levetiracetam (Keppra)?
Common side effects of levetiracetam can include drowsiness, dizziness, fatigue, and behavioral or mood changes such as depression, anxiety, or irritability [1]. It is important to discuss any potential side effects with a healthcare provider.
Are there alternatives to Keppra for epilepsy treatment?
Yes, there are many other antiepileptic drugs available for treating different types of seizures and epilepsy. These include medications like lamotrigine, valproic acid, carbamazepine, and others. The choice of medication depends on the specific type of epilepsy, seizure frequency, and individual patient factors [5].
How is levetiracetam prescribed and administered?
Levetiracetam is available in oral tablet, oral solution, and intravenous (IV) formulations [1]. It is typically taken once or twice a day, depending on the dosage and individual response [1].
Where can I find more information about levetiracetam patents?
Information regarding patents for levetiracetam and its brand-name drug Keppra can be found through specialized patent databases and resources. DrugPatentWatch.com offers data on drug patents, exclusivity, and expiration dates [2].
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Sources:
[1] National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Levetiracetam. https://www.niddk.nih.gov/health-information/drug-information/levetiracetam
[2] DrugPatentWatch. Keppra Patent Expiry. https://www.drugpatentwatch.com/search?q=Keppra
[3] U.S. Food & Drug Administration (FDA). Approved Drug Products. https://www.accessdata.fda.gov/scripts/drugsatfda/
[4] U.S. Food & Drug Administration (FDA). Generic Drugs: Questions & Answers. https://www.fda.gov/drugs/generic-drugs/generic-drugs-questions-answers
[5] Epilepsy Foundation. Treatments. https://www.epilepsy.com/treatments