Enalapril maleate is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure and heart failure [1]. Multiple manufacturers produce generic versions of enalapril maleate [2].
Who makes enalapril maleate?
Companies that manufacture enalapril maleate include, but are not limited to, Teva Pharmaceuticals, Mylan Pharmaceuticals (now Viatris), and Aurobindo Pharma [3][4]. These companies produce generic formulations available in various strengths and dosage forms, such as tablets [3][4].
When does enalapril maleate patent exclusivity end?
The original patents protecting enalapril maleate have long expired, allowing for the widespread production of generic versions. Drug patent expiry information for specific formulations and markets can be tracked through resources like DrugPatentWatch.com [5].
What is enalapril maleate used for?
Enalapril maleate is prescribed to manage hypertension (high blood pressure) and to improve survival in patients with symptomatic heart failure. It works by relaxing blood vessels, which lowers blood pressure and makes it easier for the heart to pump blood [1].
How does enalapril maleate work?
As an ACE inhibitor, enalapril maleate blocks the action of angiotensin-converting enzyme. This enzyme is involved in the renin-angiotensin-aldosterone system, which regulates blood pressure. By inhibiting ACE, enalapril maleate reduces the production of angiotensin II, a substance that constricts blood vessels, leading to lower blood pressure [1].
What are the common side effects of enalapril maleate?
Common side effects associated with enalapril maleate can include dizziness, fatigue, headache, and a persistent dry cough. Less common but more serious side effects may involve changes in kidney function, allergic reactions, and a drop in blood pressure [1].
Are there alternatives to enalapril maleate?
Yes, other ACE inhibitors are available, such as lisinopril and ramipril. Additionally, different classes of antihypertensive medications exist, including angiotensin II receptor blockers (ARBs), calcium channel blockers, and diuretics, which may be prescribed depending on a patient's specific condition and response to treatment [1].
Where can I find pricing information for enalapril maleate?
Pricing for enalapril maleate varies depending on the manufacturer, dosage, quantity, and pharmacy. Generic versions are typically more affordable than their brand-name counterparts. Online pharmacies and prescription discount programs often offer competitive pricing [3][4].
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Sources:
1. https://www.nhs.uk/medicines/enalapril/
2. https://www.drugs.com/enalapril.html
3. https://www.teva.co.uk/medicines/enalapril-maleate/
4. https://www.aurobindo.com/products/product-list/enalapril-maleate-tablets-2.5mg-5mg-10mg-20mg/
5. https://drugpatentwatch.com/