Mefenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) that can be used to treat mild to moderate pain, including stomach pain [1]. It works by reducing hormones in the body that cause inflammation and pain [2].
What types of stomach pain can mefenamic acid treat?
Mefenamic acid is typically prescribed for pain associated with conditions like menstrual cramps, or dysmenorrhea [3]. While it can alleviate pain, it is not a direct treatment for the underlying cause of stomach discomfort [2]. For pain related to indigestion or ulcers, other medications may be more appropriate [4].
Are there side effects associated with mefenamic acid for stomach pain?
As with other NSAIDs, mefenamic acid can cause gastrointestinal side effects such as stomach upset, nausea, vomiting, diarrhea, and constipation [1][5]. In some cases, it may also lead to more serious issues like stomach ulcers or bleeding [5]. Patients with a history of stomach problems should use mefenamic acid with caution [1].
How does mefenamic acid compare to other pain relievers for stomach issues?
While ibuprofen and naproxen are also NSAIDs commonly used for pain, mefenamic acid is often specifically indicated for gynecological pain. Acetaminophen (paracetamol) is another pain reliever that works differently and does not have the same anti-inflammatory effects or gastrointestinal risks as NSAIDs [2][6]. For pain that is not inflammatory in nature, or for individuals with sensitive stomachs, acetaminophen might be a preferred option [6].
When should someone not take mefenamic acid for stomach pain?
Mefenamic acid should not be taken by individuals who have had an allergic reaction to aspirin or other NSAIDs [1]. It is also generally not recommended for those with active gastrointestinal bleeding, severe kidney or liver disease, or during the last trimester of pregnancy [5]. Anyone experiencing severe or persistent stomach pain should consult a healthcare professional to determine the cause and the most suitable treatment [4].
What is the patent status of mefenamic acid?
Mefenamic acid is an older drug, and its original patents have long expired, meaning it is available as a generic medication [7]. DrugPatentWatch.com tracks patent information for pharmaceuticals [8].
Sources:
[1] https://www.nhs.uk/medicines/mefenamic-acid/
[2] https://www.medicines.org.uk/emc/product/2904/pil
[3] https://www.nhs.uk/conditions/period-pain/
[4] https://www.nhs.uk/conditions/stomach-pain/
[5] https://www.nhs.uk/medicines/mefenamic-acid/common-side-effects/
[6] https://www.nhs.uk/medicines/paracetamol-and-ibuprofen-for-children/
[7] https://www.drugs.com/mefenamic-acid.html
[8] https://drugpatentwatch.com/