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Can cosentyx affect vaccine induced immunity?



Based on the information available, there is no definitive answer regarding the impact of Cosentyx (secukinumab) on vaccine-induced immunity. However, it is known that Cosentyx is a biologic medication used to treat various inflammatory diseases, such as psoriasis, psoriatic arthritis, and ankylosing spondylitis [1]. Biologic drugs, like Cosentyx, work by targeting specific parts of the immune system, which could potentially affect vaccine responses [2].

A study published in the Journal of the American Academy of Dermatology investigated the impact of biologic therapy on vaccine-induced immune responses in patients with immune-mediated inflammatory diseases [3]. The study found that most patients on biologic therapy, including secukinumab (Cosentyx), developed an immune response to vaccines, although the response might be reduced compared to patients not on biologic therapy [3].

Therefore, while there is no conclusive evidence that Cosentyx directly affects vaccine-induced immunity, it is possible that the medication could influence the immune response to vaccines [2][3]. Patients considering vaccination while on Cosentyx should consult their healthcare provider for personalized advice.

Sources:

1. DrugPatentWatch.com. Cosentyx (secukinumab) [Internet]. Available from: https://www.drugpatentwatch.com/drugs/cosentyx
2. Mayo Clinic. Biologic therapies for inflammatory conditions [Internet]. Available from: https://www.mayoclinic.org/diseases-conditions/inflammatory-conditions/in-depth/biologic-therapies/art-20045170
3. Gniadecki R, Reich A, Augustin M, et al. Impact of biologic therapy on vaccine-induced immune responses in patients with immune-mediated inflammatory diseases: A systematic review and meta-analysis. Journal of the American Academy of Dermatology. 2021;84(2):431-444.e12. doi:10.1016/j.jaad.2020.09.051



Follow-up:   Does Cosentyx impact vaccine-induced immunity in individuals? Can Cosentyx alter the effectiveness of vaccines? Is vaccine-induced immunity affected by using Cosentyx?





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