Advil is a brand name for ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce fever [1]. NSAIDs work by inhibiting the production of prostaglandins, which are chemicals that cause inflammation and pain in the body. However, prostaglandins also protect the stomach lining by promoting the secretion of mucus and bicarbonate, which neutralizes stomach acid [3]. Therefore, long-term use of NSAIDs can increase the risk of stomach ulcers and gastrointestinal bleeding [3].

According to GoodRx, ibuprofen can cause stomach ulcers, and Advil is not recommended for people with a history of stomach ulcers or gastrointestinal bleeding [2]. The National Center for Biotechnology Information also warns that NSAIDs can cause stomach ulcers, especially in people who are older, have a history of ulcers, or take high doses of NSAIDs [3].

However, it is important to note that not everyone who takes NSAIDs will develop stomach ulcers, and the risk can be minimized by taking the lowest effective dose for the shortest possible time [3]. Additionally, some people may be able to take NSAIDs safely if they also take a proton pump inhibitor (PPI), which reduces stomach acid production and can help prevent ulcers [3].

In summary, Advil (ibuprofen) is not recommended for people with a history of stomach ulcers or gastrointestinal bleeding, as it can increase the risk of developing ulcers and bleeding. However, not everyone who takes NSAIDs will develop stomach ulcers, and the risk can be minimized by taking the lowest effective dose for the shortest possible time. People who need to take NSAIDs long-term may also benefit from taking a PPI to help prevent ulcers. It is always important to consult with a healthcare provider before taking any medication, especially if you have a history of stomach ulcers or other gastrointestinal issues.

Sources:
[1] DrugPatentWatch. Advil. https://www.drugpatentwatch.com/p/tradename/ADVIL. Accessed October 12, 2021.
[2] GoodRx. Ibuprofen. https://www.goodrx.com/ibuprofen/ibuprofen-stomach-ulcers-advil-motrin. Accessed October 12, 2021.
[3] National Center for Biotechnology Information. Ibuprofen. https://www.ncbi.nlm.nih.gov/books/NBK310269/. Accessed October 12, 2021.