What is the maintenance dose of Cosentyx (secukinumab)?
Cosentyx (secukinumab) maintenance dosing depends on the condition being treated and the body-weight category (for plaque psoriasis, dosing is fixed by condition, not weight).
Plaque psoriasis (adult)
After the initial dosing phase, the maintenance dose is:
- 300 mg by subcutaneous injection every 4 weeks.
Cosentyx is also available as a lower-dose maintenance option in some dosing regimens:
- 150 mg by subcutaneous injection every 4 weeks (used in certain situations based on the prescribed regimen).
Psoriatic arthritis (adult)
The maintenance dose is:
- 150 mg by subcutaneous injection every 4 weeks, or
- 300 mg every 4 weeks (when a higher regimen is prescribed).
Ankylosing spondylitis (adult)
The maintenance dose is:
- 150 mg by subcutaneous injection every 4 weeks, or
- 300 mg every 4 weeks (when a higher regimen is prescribed).
Non-radiographic axial spondyloarthritis (adult)
The maintenance dose is:
- 150 mg by subcutaneous injection every 4 weeks.
Crohn’s disease (adult)
Maintenance dosing is typically:
- 300 mg by subcutaneous injection every 4 weeks.
Ulcerative colitis (adult)
Maintenance dosing is typically:
- 300 mg by subcutaneous injection every 4 weeks, or
- 150 mg every 4 weeks depending on the prescribed regimen.
How does Cosentyx maintenance dosing differ from the starting dose?
Cosentyx induction (starting) dosing is more frequent in the first weeks, and the maintenance phase shifts to once every 4 weeks. The exact induction schedule varies by condition, but the maintenance interval is commonly every 4 weeks.
What happens if you miss a Cosentyx maintenance dose?
If you miss a dose, the practical approach is usually to take it as soon as you remember and then resume the regular schedule. Because timing guidance can vary by how late the dose is, your prescriber/pharmacist should confirm what to do for your specific situation.
Can the maintenance dose be increased or decreased?
Yes. Prescribers may adjust maintenance dosing (for example, between 150 mg and 300 mg every 4 weeks) depending on the condition, response, and tolerability.
If you tell me which condition you’re treating (plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, Crohn’s, or ulcerative colitis) and whether your prescription is 150 mg or 300 mg, I can restate the exact maintenance schedule for that scenario.