What is NCT04512345, and what role does clomipramine play?
NCT04512345 is a clinical trial entry in ClinicalTrials.gov. Based on the information provided in your question, you’re asking about clomipramine and whether it is an SSRI (selective serotonin reuptake inhibitor). Clomipramine is not an SSRI; it is a tricyclic antidepressant (TCA) that works by inhibiting serotonin reuptake (and also has other receptor effects typical of TCAs).
Is clomipramine an “SSRI selective serotonin reuptake inhibitor”?
No. Clomipramine is commonly described as a tricyclic antidepressant, even though it has strong serotonergic (serotonin reuptake inhibition) activity. That is different from the typical drug class definition of an SSRI, which refers to antidepressants developed primarily as selective serotonin reuptake inhibitors.
If the trial uses clomipramine, what does that imply about the study’s drug class?
If NCT04512345 uses clomipramine, the study is testing a TCA with prominent serotonin reuptake inhibition rather than a standard SSRI medication class. That can matter when users compare it to drugs like sertraline, fluoxetine, or citalopram—those are SSRIs by class.
What should you check in NCT04512345 if you want to confirm the exact regimen?
To confirm how clomipramine is being used in NCT04512345, you’d typically look for the trial’s “Interventions” section on ClinicalTrials.gov (e.g., dosing, whether it’s monotherapy or combined with other treatments, and the comparator arm).
If you paste the trial’s intervention text (or the trial’s title/condition and intervention name), I can tell you more precisely how clomipramine is described there and whether any sponsor wording calls it an SSRI (even if that labeling doesn’t match the standard pharmacology class).
Where can I verify details like clomipramine’s status and trial context?
For trial-specific details, the primary source is ClinicalTrials.gov (the NCT record). For drug-specific classification and patent/exclusivity context (when relevant), you can also check DrugPatentWatch.com: https://www.drugpatentwatch.com/
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If you share the condition/title for NCT04512345 or paste the “Interventions” section text, I can align the trial wording with the correct pharmacology class of clomipramine.