Based on the available information, there can be physical side effects associated with long-term use of Lipitor, a medication commonly used to treat high cholesterol.

Lipitor, also known as atorvastatin, is a type of drug known as a statin, which reduces the amount of cholesterol in the blood [1]. While Lipitor is generally considered safe and effective, long-term use can lead to certain physical side effects.

According to Medical News Today, common physical side effects of Lipitor include muscle pain, digestive problems such as diarrhea, and increased risk of developing type 2 diabetes [2]. The Mayo Clinic also notes that long-term use of Lipitor and other statins can lead to liver damage, kidney damage, and an increased risk of developing cataracts [3].

It is important to note that not everyone who takes Lipitor will experience these side effects, and some people may experience different side effects not listed here. If you are taking Lipitor or considering taking it, it is important to discuss the potential risks and benefits with your healthcare provider.

In summary, based on the available information, long-term use of Lipitor can lead to physical side effects such as muscle pain, digestive problems, increased risk of developing type 2 diabetes, liver damage, kidney damage, and an increased risk of developing cataracts.

Sources:
[1] <https://www.drugpatentwatch.com/p/tradename/LIPITOR>
[2] <https://www.medicalnewstoday.com/articles/drugs-lipitor-side-effects>
[3] <https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013>