What is the recommended acyclovir dosage for adults (by condition)?
Recommended dosing depends on what infection is being treated and kidney function. Common adult regimens include:
- Herpes simplex (HSV) infections
- Treatment of genital herpes (first episode or recurrences): 200 mg 5 times daily for 7–10 days, or 400 mg 3 times daily for 7–10 days.
- Suppressive therapy for recurrent genital herpes: 400 mg 2 times daily.
- Herpes zoster (shingles)
- 800 mg 5 times daily for 7–10 days.
How is acyclovir dosed in children?
Pediatric dosing is also based on the specific diagnosis and typically adjusted for weight and age. Many regimens are weight-based (mg/kg) rather than using the adult fixed dose, especially for HSV or varicella (chickenpox). Kidney function affects dosing as well.
What if the patient has kidney problems?
Acyclovir is cleared by the kidneys. If kidney function is reduced, clinicians typically lower the dose and/or increase the dosing interval to avoid drug accumulation and toxicity.
Does acyclovir dosage differ for oral vs. IV?
Yes. IV acyclovir is used for more severe infections (for example, certain encephalitis, disseminated infections, or when oral dosing isn’t possible). IV regimens are different from oral dosing and are selected based on indication and kidney function.
What should you check before taking acyclovir?
Before following any dosage, confirm:
- the exact diagnosis (HSV vs zoster vs varicella, etc.)
- whether the prescription is for treatment or suppression
- the patient’s age/weight
- kidney function (serum creatinine/eGFR)
- whether the prescription uses oral tablets/capsules, suspension, or IV
Quick clarification so I can give the exact dose
Which one do you need dosing for: genital herpes (treatment vs daily suppression), oral herpes, shingles, chickenpox, or something else—and is it for an adult or a child (age/weight), with known kidney disease?