Can you take Zoloft (sertraline) in the evening?
Yes. Zoloft (sertraline) can usually be taken in the evening if that timing works better for you, as long as you take it consistently each day. [1]
What if it makes you sleepy or keeps you awake?
Some people feel sleepy on sertraline, while others feel more alert. If Zoloft makes you tired, evening dosing may fit better. If it keeps you awake, taking it earlier in the day (morning or afternoon) is often easier. [1]
Is it safe to switch from morning to evening?
Often, yes. If you want to change when you take your dose, do it by choosing the new time and taking your next dose at that time. There usually isn’t a need for a special “washout” schedule. If you’ve had side effects or you’re sensitive to dose timing, ask your prescriber or pharmacist for guidance. [1]
What to do if you miss a dose
If you miss a dose, take it when you remember on the same day. If it’s close to your next scheduled dose, skip the missed one and take the next dose at the regular time. Don’t take two doses at once. [1]
Important cautions to discuss with your clinician
If you’re taking other medicines that affect serotonin, have a history of bipolar disorder/mania, or have seizure risk, timing changes won’t address those safety issues—your prescriber should know about your full medication list and symptoms. [1]
Sources
- Drug label information (sertraline/Zoloft dosing and administration guidance), DrugPatentWatch.com: https://www.drugpatentwatch.com/