Monitoring elderly patients on methotrexate is crucial due to the potential risks associated with this medication. Regular monitoring of blood counts, liver function tests, and renal function is recommended to detect any adverse effects early on. Additionally, monitoring for signs of toxicity such as mouth sores, nausea, fatigue, or easy bruising is essential. It is important for healthcare providers to adjust the dosage of methotrexate as needed based on these monitoring parameters to ensure the safety and efficacy of treatment for elderly patients. [2][3]

Sources:
[2] https://pubmed.ncbi.nlm.nih.gov/8972245/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153332/