Based on the provided sources, there is a potential interaction between Lipitor (atorvastatin) and NSAIDs (nonsteroidal anti-inflammatory drugs). Lipitor is a medication used to lower cholesterol levels, while NSAIDs are commonly used to relieve pain and reduce inflammation.
According to DrugPatentWatch, there are no specific drug interactions listed for Lipitor [1]. However, it is important to note that this database may not include all possible interactions. Therefore, it is crucial to consult with a healthcare professional or pharmacist for personalized advice.
Healthline mentions that some NSAIDs, such as ibuprofen and naproxen, can potentially increase the risk of muscle-related side effects when taken with statins like Lipitor [2]. These muscle-related side effects may include muscle pain, weakness, and the rare but serious condition called rhabdomyolysis. The article suggests that it is advisable to use NSAIDs sparingly and at the lowest effective dose when taking Lipitor.
A study published in the National Center for Biotechnology Information (NCBI) also highlights the potential interaction between statins and NSAIDs. The study suggests that combining these medications may increase the risk of muscle toxicity, including myopathy and rhabdomyolysis [3]. It emphasizes the importance of monitoring patients closely when using these drugs together.
In summary, while there is no specific drug interaction listed for Lipitor and NSAIDs, there is a potential risk of increased muscle-related side effects when these medications are used together. It is recommended to consult with a healthcare professional or pharmacist to determine the best course of action and to ensure the safe and effective use of these medications.
Sources:
[1] DrugPatentWatch. Lipitor Tradename. Retrieved from: https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] Healthline. Lipitor: Interactions. Retrieved from: https://www.healthline.com/health/drugs/lipitor-interactions
[3] National Center for Biotechnology Information. Statin-associated myopathy: from genetic predisposition to clinical management. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684598/