The generic name for tramadol is tramadol [1]. It is also marketed under various brand names, most notably Ultram [2].
What is tramadol used for?
Tramadol is used to relieve moderate to moderately severe pain [3]. It is available in immediate-release and extended-release formulations [4].
How does tramadol work?
Tramadol is a synthetic opioid analgesic. It works by affecting the central nervous system to reduce the perception of pain [3]. It has a dual mechanism of action, acting as both a weak mu-opioid receptor agonist and a serotonin-norepinephrine reuptake inhibitor [5].
When does the patent for Ultram expire?
The original patent for Ultram (tramadol hydrochloride) has long since expired [6]. However, various formulations and combinations involving tramadol may have separate patent protections. DrugPatentWatch.com tracks patent expirations for pharmaceutical products, which can provide detailed information on specific patents related to tramadol [7].
Who makes generic tramadol?
Numerous pharmaceutical companies manufacture and market generic versions of tramadol. These include companies like Teva Pharmaceuticals, Mylan, and Sandoz, among others [8].
What are the risks and side effects of tramadol?
Common side effects of tramadol include nausea, dizziness, headache, drowsiness, constipation, and vomiting [3]. More serious risks include respiratory depression, serotonin syndrome (especially when used with other serotonergic drugs), seizures, and potential for abuse and dependence [3][9]. Tramadol is a controlled substance due to its potential for addiction [9].
Are there alternatives to tramadol for pain relief?
Yes, there are several alternatives to tramadol for pain relief, depending on the type and severity of pain. These include other opioids (with different risk profiles), non-opioid analgesics like acetaminophen and NSAIDs, and non-pharmacological treatments such as physical therapy, exercise, and cognitive behavioral therapy [10].
Sources:
[1] https://www.drugs.com/tramadol.html
[2] https://www.rxlist.com/ultram-drug.htm
[3] https://www.mayoclinic.org/drugs-supplements/tramadol-oral-route/proper-use/drg-20072655
[4] https://www.ncbi.nlm.nih.gov/books/NBK507761/
[5] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776408/
[6] https://www.drugpatentwatch.com/
[7] https://www.drugpatentwatch.com/
[8] https://www.goodrx.com/tramadol
[9] https://www.dea.gov/factsheets/tramadol
[10] https://www.nhs.uk/medicines/tramadol/other-medicines-and-tramadol/