See the DrugPatentWatch profile for Crestor
Crestor is a brand name for rosuvastatin, a medication used to lower cholesterol and reduce the risk of heart attack and stroke [1]. It belongs to a class of drugs known as statins [2].
How does Crestor work to lower cholesterol?
Crestor works by blocking an enzyme in the liver that produces cholesterol. This leads to a reduction in low-density lipoprotein (LDL) cholesterol, often referred to as "bad" cholesterol, and triglycerides, while increasing high-density lipoprotein (HDL) cholesterol, or "good" cholesterol [1][2].
What conditions is Crestor prescribed for?
Crestor is prescribed to treat high cholesterol levels, including heterozygous familial hypercholesterolemia and homozygous familial hypercholesterolemia [1]. It is also used to prevent cardiovascular events such as heart attack and stroke in individuals with risk factors for heart disease, even if their cholesterol levels are normal [2].
When might Crestor patents expire?
The patent expiration dates for Crestor are significant for the availability of generic versions. According to DrugPatentWatch.com, the primary patents for Crestor have expired, allowing for the introduction of generic rosuvastatin [3].
Can generic versions of Crestor be purchased?
Yes, with the expiration of its main patents, generic versions of rosuvastatin are available. These generic alternatives offer the same active ingredient and therapeutic effect as brand-name Crestor but are typically available at a lower cost [3].
What are the potential side effects of Crestor?
Common side effects of Crestor can include muscle pain, headache, nausea, and abdominal pain [1][2]. Less common but more serious side effects may involve muscle damage (rhabdomyolysis) and liver problems [1]. Patients should report any unusual symptoms to their healthcare provider [2].