According to the sources provided, there is no specific mention of adjusting the dosage of Lipitor (atorvastatin) after a high-fat meal. However, it is important to note that taking Lipitor with or without food does not significantly affect its absorption [2].

Lipitor is a medication commonly prescribed to lower cholesterol levels in patients with high cholesterol or other risk factors for heart disease. It belongs to a class of drugs called statins, which work by inhibiting an enzyme involved in cholesterol production in the liver [3].

The first source provided, DrugPatentWatch, provides information on the patent status of Lipitor but does not mention anything about dosage adjustments after a high-fat meal.

The second source, a study published on PubMed, focuses on the pharmacokinetics of atorvastatin when taken with grapefruit juice. The study found that grapefruit juice can increase the absorption of atorvastatin, leading to higher blood levels of the medication. However, this study does not specifically address the effect of a high-fat meal on Lipitor dosage [1].

The third source, Mayo Clinic, provides general information about Lipitor, including its uses, side effects, and precautions. While it does not mention adjusting the dosage after a high-fat meal, it does recommend taking Lipitor as directed by a healthcare professional and following a healthy diet to maximize its effectiveness [3].

In conclusion, based on the provided sources, there is no specific guidance regarding adjusting the dosage of Lipitor after a high-fat meal. It is always best to follow the instructions provided by your healthcare professional and consult with them if you have any concerns or questions about your medication regimen.

Sources:
[1] https://pubmed.ncbi.nlm.nih.gov/21269482/
[2] https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20067003?p=1
[3] https://www.drugpatentwatch.com/p/tradename/LIPITOR