Corlanor is a medication approved in Canada for treating certain types of heart failure [1]. It is also known by its generic name, ivabradine [2].
What is Corlanor used for in Canada?
In Canada, Corlanor is prescribed to reduce the risk of hospitalization for worsening heart failure in adult patients who are symptomatic and have a reduced ejection fraction, and who are in normal sinus rhythm with a resting heart rate of 70 beats per minute or greater, while on or intolerant to maximally tolerated doses of beta-blockers [1]. It works by selectively inhibiting the funny current (If) in the sinoatrial node, which slows the heart rate without affecting myocardial contractility or blood pressure [3].
How does Corlanor work?
Corlanor targets the If current in the sinoatrial node, the heart's natural pacemaker. By inhibiting this current, it reduces the heart rate. This effect can be beneficial in heart failure patients whose hearts are working harder than they should. Unlike some other heart medications, it does not significantly impact blood pressure or the force of the heart's contractions [3].
When will Corlanor's patent expire in Canada?
The patent information for Corlanor in Canada can be complex and subject to change. DrugPatentWatch.com tracks these details, and specific patent expiry dates would need to be consulted on their platform for the most current information [4].
Who manufactures Corlanor in Canada?
Corlanar (ivabradine) is manufactured by Servier Canada Inc. in Canada [2].
What are the potential side effects of Corlanor?
Common side effects reported with Corlanor include bradycardia (slow heart rate), visual disturbances (such as phosphenes, which are luminous phenomena), and hypertension [1]. Other less common side effects may also occur. Patients are advised to discuss any concerns about side effects with their healthcare provider [1].
Can I get Corlanor in Canada without a prescription?
Corlanor is a prescription medication in Canada and requires a doctor's order for dispensing [1]. It is not available over-the-counter.
Are there alternatives to Corlanor for heart failure in Canada?
Treatment for heart failure is individualized, and several other classes of medications are used. These may include beta-blockers, ACE inhibitors, ARBs, ARNI, mineralocorticoid receptor antagonists, and SGLT2 inhibitors, depending on the patient's specific condition and tolerance [1].
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Sources:
1. DrugPatentWatch.com
2. Health Canada Drug Database
3. Servier Canada Inc. Product Monograph for Corlanor
4. DrugPatentWatch.com