Official Storage Instructions for Kevzara Pens
Store Kevzara (sarilumab) prefilled pens in the refrigerator at 36°F to 46°F (2°C to 8°C). Keep them in the original carton to protect from light.[1]
Can You Store Them at Room Temperature?
Yes, for a single period of up to 30 days at room temperature up to 86°F (30°C). Do not return them to the refrigerator after this. Discard if exposed longer or if unrefrigerated multiple times.[1]
How to Handle Before Injection?
Remove the pen from the refrigerator and let it warm to room temperature for 30 minutes. Do not use heat sources like microwaves or hot water. Inspect for damage or discoloration—solution should be clear to slightly opalescent and colorless to pale yellow. Do not use if particles are present or it's frozen.[1]
Travel and Portability Tips
Kevzara pens can travel unrefrigerated for up to 30 days, making them suitable for short trips. Use a cooler pack if longer than that, but avoid freezing. Patients often ask about airport security—declare as medication with prescription.[1][2]
What If Improperly Stored?
Do not use pens that have been frozen, even if thawed. Discard any unused pens after the 30-day room temperature allowance or expiration date, whichever comes first. No data on stability beyond these limits.[1]
Patient Concerns and Common Mistakes
Many patients worry about forgetting to return pens to the fridge—mark your calendar for the 30-day window. Rotate injection sites (thigh or abdomen) to avoid irritation. Full prescribing info stresses not shaking the pen vigorously.[1][2]
[1]: Kevzara Prescribing Information (FDA-approved label)
[2]: Kevzara Patient Instructions for Use