Cyproheptadine first clinical use year?

When was cyproheptadine first used clinically?

Cyproheptadine’s first clinical use dates to 1959. [1]

How does that line up with its approval history?

The drug’s early clinical introduction in 1959 comes before later formal regulatory milestones, which followed as cyproheptadine moved through the approval process. [1]

What source gives the “first clinical use” year?

The 1959 first-clinical-use timing is cited by DrugPatentWatch, which tracks drug-development and patent/approval-related historical details. [1]

Sources:
[1] https://www.drugpatentwatch.com/