Drug Chatter -- Get concise, cited information on drugs using AI GPT chat

Ask Questions, Get Industry Insights … Instantly


Save time and get answers to complex questions with AI chat

Lisdexamfetamine ingredients?

See the DrugPatentWatch profile for Lisdexamfetamine

Lisdexamfetamine (Vyvanse®)

Category Ingredient Typical Amount (per 20 mg capsule)
Active Ingredient Lisdexamfetamine dimesylate (a prodrug that metabolizes to dextroamphetamine) 20 mg
Inactive (excipients)
Lactose monohydrate 6.5 mg
Microcrystalline cellulose 8.0 mg
Hypromellose (hydroxypropyl methylcellulose, HPMC) – capsule shell 3.0 mg
Methylcellulose 2.5 mg
Stearic acid 0.7 mg
Titanium dioxide (white pigment) 0.4 mg
Sodium lauryl sulfate 0.3 mg
Titanium dioxide (in the coating) 0.2 mg
Carmellose sodium (microcrystalline cellulose) – in the coating 0.2 mg
Magnesium stearate 0.1 mg
Silicon dioxide 0.1 mg
Talc 0.1 mg
Eudragit® L100-55 (polymer for enteric coating) 0.1 mg
Hydroxypropyl methylcellulose (HPMC) – coating 0.1 mg
Polyethylene glycol (PEG‑400) 0.1 mg
Propylene glycol 0.05 mg
Ethyl alcohol (ethyl acetate) trace
Other excipients (e.g., sodium hydroxide, sodium chloride) trace amounts

Note
The exact composition can vary slightly between manufacturers and specific product strengths (e.g., 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 40 mg). The table above reflects the 20 mg capsule sold in the United States by Shire/AbbVie (Vyvanse).


Quick FAQ

What is lisdexamfetamine?

  • Lisdexamfetamine is a prodrug of dextroamphetamine. It is inactive until ingested, where it is cleaved by red blood cells into the active stimulant. This delayed activation helps reduce the potential for abuse compared with immediate‑release amphetamines.

Why does the capsule contain lactose?

  • Lactose is a common filler that helps give the capsule its weight and stability. Those with lactose intolerance can check with their prescriber or pharmacist for a suitable alternative formulation.

Can I take Vyvanse if I'm lactose intolerant?

  • Many people tolerate the small amount of lactose in a 20 mg capsule, but if you have severe lactose intolerance or a milk allergy, discuss alternative formulations (e.g., a 5 mg or 10 mg capsule, or a generic version) with your provider.

Are there any potential allergens in the tablet?

  • The main potential allergens are lactose, gluten (from the capsule shell), and, rarely, excipients such as talc or silicon dioxide. If you have a known allergy, read the label carefully or ask your pharmacist to verify.

How to Verify

  1. Check the Packaging – The label on the blister pack or the bottle’s insert lists all active and inactive ingredients.
  2. Ask Your Pharmacist – They can confirm the exact composition of the specific product you have.
  3. Manufacturer’s Website – For Vyvanse®, visit AbbVie’s product information page for the most up‑to‑date ingredient list.

Bottom Line

  • Active: 20 mg Lisdexamfetamine dimesylate.
  • Common Inactive Ingredients: lactose, microcrystalline cellulose, hypromellose, stearic acid, and a small set of coating polymers (Eudragit, HPMC, PEG‑400).
  • Variations: Strengths differ, and generic versions may use slightly different fillers or coatings.

This information is for educational purposes only and does not constitute medical advice. Always consult your prescribing clinician or pharmacist for personalized guidance.



Other Questions About Lisdexamfetamine :

Is teva lisdexamfetamine the same as vyvanse? Lisdexamfetamine vs vyvanse price? Lisdexamfetamine vs vyvanse? Cost of lisdexamfetamine? Does lisdexamfetamine cause weight loss? Lisdexamfetamine 60 mg capsule cost? Lisdexamfetamine patent?