Has pfizer lost their patent on eliquis?

Yes—Eliquis (apixaban) is no longer protected by Pfizer’s original U.S. patent for the drug substance, so generic versions are available in the U.S.

However, patent “status” is more complicated than one yes/no, because:

• There can be other, later-expiring patents (e.g., about specific formulations, dosing regimens, or manufacturing), which may affect certain generic approvals or brand protections in some markets.
• In the U.S., generic and other manufacturer versions are generally on the market because the core patent protections have expired and regulatory pathways (like Abbreviated New Drug Applications) have been used.

If you tell me what country you’re in (US/UK/EU/etc.) and whether you mean tablet strength (e.g., 2.5 mg vs 5 mg), I can give a more specific, up-to-date answer.