Opzelura cream ingredients?

Opzelura (Topical Ruxolitinib 1.5 % Cream)
This is the formulation that is sold in the United States (the brand‑name product is called Opzelura). The list below is taken from the FDA prescribing information and the product label. If you have a question about a specific ingredient or a possible allergen, be sure to check the actual bottle you have or consult your pharmacist. Formulations can differ by region or over time.

---

Active Ingredient

| Ingredient | Strength (in the cream) |
|------------|------------------------|
| Ruxolitinib | 1.5 % w/w (0.5 mg per 2 g of cream) |

---

Inactive (excipients)

(listed in no particular order; amounts are in order of predominance as usually shown on the label)

| Ingredient | Common Function | Typical Use in the Cream |
|------------|-----------------|--------------------------|
| Water (H₂O) | Solvent | Primary vehicle |
| Propylene Glycol | Humectant / solvent | Helps dissolve active drug |
| Butylene Glycol | Humectant / solvent | Improves spreadability |
| 1,2‑Hexanediol | Emollient / preservative enhancer | Enhances skin penetration |
| Glycerin (Glycerol) | Humectant | Keeps skin moisturised |
| PEG‑400 (Polyethylene Glycol‑400) | Solvent / viscosity modifier | Helps keep active drug evenly dispersed |
| Polysorbate 20 | Emulsifier | Keeps oil and water phases mixed |
| Polysorbate 80 | Emulsifier / solubiliser | Works with polysorbate 20 for stability |
| Cetyl Alcohol | Emollient / thickening agent | Gives the cream its creamy texture |
| Stearyl Alcohol | Emollient / thickener | Adds body to the cream |
| Glyceryl Monostearate | Emulsifier | Helps form a stable emulsion |
| PEG‑8 (Polyethylene Glycol‑8) | Emulsifier | Works with glyceryl monostearate |
| Triethyl Citrate | Preservative / emollient | Stabilises the formulation |
| Disodium EDTA | Chelating agent | Improves preservative efficacy |
| Triisopropylsiloxyethyl Cetyl Phosphate | Emulsifier / solubiliser | Helps solubilise ruxolitinib |
| Isopropyl Myristate | Emollient | Enhances skin absorption |
| 1,2‑Propandiol |