When taking Lipitor (atorvastatin), a medication used to treat high cholesterol, it's important to consider how antacids might interact with it. Antacids can affect the absorption of Lipitor in the body.

Lipitor is typically taken in the evening [1]. Antacids, on the other hand, are usually taken when needed, often after meals or at bedtime [2]. If you're taking Lipitor and antacids at the same time, it's recommended to take the antacid at least one hour after taking Lipitor [1]. This allows sufficient time for Lipitor to be absorbed into your system before the antacid is taken.

However, it's always best to consult with your healthcare provider or pharmacist for personalized advice. They can provide guidance based on your specific medications, dosages, and health conditions.

Sources:
[1] "Atorvastatin Calcium Tablets, USP Rx only." DailyMed, National Library of Medicine, database.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0156df3e-d62e-4e2e-a5b2-f8d36dd6e1f7.
[2] "Antacids: Over-the-Counter Relief for Heartburn and Acid Indigestion." Mayo Clinic, Mayo Foundation for Medical Education and Research, 11 Jan. 2022, www.mayoclinic.org/diseases-conditions/heartburn/in-depth/antacids/art-20046641.