Based on the information provided, the combination of Lipitor and diuretics can be safe when used under a healthcare professional's supervision. Both Lipitor (atorvastatin) and diuretics are commonly used to treat high blood pressure and cardiovascular diseases [1, 3]. Lipitor is a statin that lowers cholesterol levels, while diuretics help reduce the amount of fluid in the body by increasing urine production [1][3].

However, combining these medications can have potential risks due to possible drug interactions. According to the National Center for Biotechnology Information (NCBI), combining statins like Lipitor with diuretics can increase the risk of developing muscle adverse effects, such as rhabdomyolysis [2]. Rhabdomyolysis is a serious condition that can lead to kidney damage and other complications [2].

It is essential to consult a healthcare professional before combining these medications, as they can monitor the patient's condition and adjust the treatment plan accordingly. Healthcare professionals may consider alternative medications or lower dosages to minimize the risk of adverse effects [2].

In summary, while combining Lipitor and diuretics can have potential risks, these medications can be used safely under a healthcare professional's supervision. Patients should consult their healthcare provider before starting or changing any medication.

Sources:
[1] <https://www.drugpatentwatch.com/p/tradename/LIPITOR>
[2] <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537141/>
[3] <https://www.heart.org/en/health-topics/heart-attack/treatment-of-a-heart-attack/cardiac-medications>