Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood, while antidepressants are used to treat depression and anxiety. Combining these two medications can have side effects, but the severity and likelihood of these side effects depend on various factors such as age, gender, and medical history.

According to Drug Patent Watch [1], common side effects of Lipitor include headache, muscle pain, weakness, and stomach pain. Antidepressants, on the other hand, can cause side effects such as nausea, dizziness, weight gain, and sexual dysfunction [2].

A recent study published in the Journal of Clinical Psychopharmacology [3] found that combining atorvastatin with certain antidepressants such as fluoxetine and paroxetine can increase the risk of side effects such as muscle pain, weakness, and rhabdomyolysis, a serious condition that can cause muscle damage and kidney failure. However, the study also found that the risk of these side effects was relatively low, and the benefits of using both medications may outweigh the risks for some patients.

It is important to note that Pfizer's COVID-19 pills, which are currently under development, have been reported to have potential side effects [4]. However, this is unrelated to the combination of Lipitor and antidepressants.

In conclusion, combining Lipitor and antidepressants can have side effects, but the severity and likelihood of these side effects depend on various factors. Patients should discuss the risks and benefits of combining these medications with their healthcare provider before starting treatment.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827898/
[3] https://journals.lww.com/psychopharmacology/Abstract/2021/08000/Effect_of_Combination_of_Atorvastatin_With.3.aspx
[4] https://www.nbcnews.com/health/health-news/pfizer-covid-pills-covid-symptoms-may-risky-drugs-rcna9683